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Functional characterization of natural variants found on the major stress inducible 70-kDa heat shock gene, HSPA1A, in humans
In this report, we investigated the effects of natural single nucleotide polymorphisms on the function of HSPA1A, the major stress-inducible Hsp70 gene in humans. We first established that all mutant proteins retain their ability to hydrolyze ATP, but three of them had a significantly lower rate of...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277039/ https://ncbi.nlm.nih.gov/pubmed/30384997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.10.148 |
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