Increases in IGF-1 After Anti–TNF-α Therapy Are Associated With Bone and Muscle Accrual in Pediatric Crohn Disease

CONTEXT: Low levels of insulinlike growth factor 1 (IGF-1) in pediatric and adolescent Crohn disease (CD) likely contribute to bone and muscle deficits. OBJECTIVE: Assess changes in IGF-1 levels and associations with bone and muscle accrual following initiation of anti–tumor necrosis factor α (TNF-α...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: DeBoer, Mark D, Lee, Arthur M, Herbert, Kirabo, Long, Jin, Thayu, Meena, Griffin, Lindsay M, Baldassano, Robert N, Denson, Lee A, Zemel, Babette S, Denburg, Michelle R, Herskovitz, Rita, Leonard, Mary B
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276706/
https://ncbi.nlm.nih.gov/pubmed/29329430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-01916
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