In silico VHL Gene Mutation Analysis and Prognosis of Pancreatic Neuroendocrine Tumors in von Hippel–Lindau Disease

CONTEXT: Patients with von Hippel–Lindau (vHL) disease caused by a missense VHL mutation have a more severe phenotype compared with other VHL mutation types. OBJECTIVE: To define pancreatic neuroendocrine tumor (PNET) aggressiveness according to VHL genotype. DESIGN: A prospective natural history st...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Tirosh, Amit, el Lakis, Mustapha, Green, Patience, Nockel, Pavel, Patel, Dhaval, Nilubol, Naris, Gara, Sudheer Kumar, Keutgen, Xavier M, Linehan, W Marston, Kebebew, Electron
Format: Artigo
Language:Inglês
Published: Endocrine Society 2017
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Clinical Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276699/
https://ncbi.nlm.nih.gov/pubmed/29294023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-02434
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