Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide

STUDY QUESTION: Can maternal and offspring high-fat diet (HFD)-induced changes in mRNA expression levels in mice be ameliorated by interventions in female offspring? SUMMARY ANSWER: Our results indicate that exercise and nicotinamide mononucleotide (NMN) can ameliorate the negative effects of matern...

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Detalhes bibliográficos
Publicado no:Hum Reprod Open
Main Authors: Bertoldo, M J, Uddin, G M, Youngson, N A, Agapiou, D, Walters, K A, Sinclair, D A, Morris, M J, Gilchrist, R B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276682/
https://ncbi.nlm.nih.gov/pubmed/30895251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hropen/hoy010
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