rs10732516 polymorphism at the IGF2/H19 locus associates with a genotype-specific trend in placental DNA methylation and head circumference of prenatally alcohol-exposed newborns

STUDY QUESTION: Does prenatal alcohol exposure (PAE) affect regulation of the insulin-like growth factor 2 (IGF2)/H19 locus in placenta and the growth-restricted phenotype of newborns? SUMMARY ANSWER: PAE results in genotype-specific trends in both placental DNA methylation at the IGF2/H19 locus and...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hum Reprod Open
Päätekijät: Marjonen, Heidi, Kahila, Hanna, Kaminen-Ahola, Nina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276671/
https://ncbi.nlm.nih.gov/pubmed/30895230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hropen/hox014
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