Uric Acid Protects against Focal Cerebral Ischemia/Reperfusion-Induced Oxidative Stress via Activating Nrf2 and Regulating Neurotrophic Factor Expression

The aim of this study was to investigate whether uric acid (UA) might exert neuroprotection via activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway and regulating neurotrophic factors in the cerebral cortices after transient focal cerebral ischemia/reperfusion (FCI/R) in rats....

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ya, Bai-liu, Liu, Qian, Li, Hong-fang, Cheng, Hong-ju, Yu, Ting, Chen, Lin, Wang, You, Yuan, Li-li, Li, Wen-juan, Liu, Wen-yan, Bai, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276484/
https://ncbi.nlm.nih.gov/pubmed/30581534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6069150
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