Novel spheroid reservoir bioartificial liver improves survival of nonhuman primates in a toxin-induced model of acute liver failure

This study aims to evaluate the effectiveness and safety of the spheroid reservoir bioartificial liver (SRBAL) with porcine hepatocyte organoids in a preclinical nonhuman primate model of acute liver failure (ALF). Methods: Thirty healthy rhesus monkeys were infused with α-amanitin and lipopolysacch...

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Bibliographic Details
Published in:Theranostics
Main Authors: Li, Yi, Wu, Qiong, Wang, Yujia, Weng, Chengxin, He, Yuting, Gao, Mengyu, Yang, Guang, Li, Li, Chen, Fei, Shi, Yujun, Amiot, Bruce P., Nyberg, Scott L., Bao, Ji, Bu, Hong
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276288/
https://ncbi.nlm.nih.gov/pubmed/30555564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.26540
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