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Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells

Axons fail to regenerate in the adult central nervous system (CNS) following injury. Developing strategies to promote axonal regeneration is therapeutically attractive for various CNS pathologies such as traumatic brain injury, stroke and Alzheimer’s disease. Because the RhoA pathway is involved in...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Zhang, Zhiqun, Ottens, Andrew K., Larner, Stephen F., Kobeissy, Firas H., Williams, Melissa L., Hayes, Ronald L., Wang, Kevin K. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Versita 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276008/
https://ncbi.nlm.nih.gov/pubmed/16847745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-006-0002-x
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