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Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells

Axons fail to regenerate in the adult central nervous system (CNS) following injury. Developing strategies to promote axonal regeneration is therapeutically attractive for various CNS pathologies such as traumatic brain injury, stroke and Alzheimer’s disease. Because the RhoA pathway is involved in...

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Bibliografische gegevens
Gepubliceerd in:Cell Mol Biol Lett
Hoofdauteurs: Zhang, Zhiqun, Ottens, Andrew K., Larner, Stephen F., Kobeissy, Firas H., Williams, Melissa L., Hayes, Ronald L., Wang, Kevin K. W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Versita 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276008/
https://ncbi.nlm.nih.gov/pubmed/16847745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-006-0002-x
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