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Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes

Previous studies have demonstrated that ocular injury can lead to prompt infiltration of bone-marrow–derived peripheral monocytes into the retina. However, the ability of these cells to integrate into the tissue and become microglia has not been investigated. Here we show that such peripheral monocy...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Paschalis, Eleftherios I., Lei, Fengyang, Zhou, Chengxin, Kapoulea, Vassiliki, Dana, Reza, Chodosh, James, Vavvas, Demetrios G., Dohlman, Claes H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275537/
https://ncbi.nlm.nih.gov/pubmed/30442669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807123115
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