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The Systems Biology of Uric Acid Transporters: The Role of Remote Sensing and Signaling
PURPOSE OF REVIEW: Uric acid homeostasis in the body is mediated by a number of SLC and ABC transporters in the kidney and intestine, including several multispecific ‘drug’ transporters (e.g., OAT1, OAT3, and ABCG2). Optimization of uric acid levels can be viewed as a ‘systems biology’ problem. Here...
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| Publié dans: | Curr Opin Nephrol Hypertens |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6275126/ https://ncbi.nlm.nih.gov/pubmed/29847376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000427 |
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