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ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning

MOTIVATION: The identification of functional sequence variations in regulatory DNA regions is one of the major challenges of modern genetics. Here, we report results of a combined multifactor analysis of properties characterizing functional sequence variants located in promoter regions of genes. RES...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Malkowska, Maja, Zubek, Julian, Plewczynski, Dariusz, Wyrwicz, Lucjan S.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275119/
https://ncbi.nlm.nih.gov/pubmed/30519505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5742
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