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ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning
MOTIVATION: The identification of functional sequence variations in regulatory DNA regions is one of the major challenges of modern genetics. Here, we report results of a combined multifactor analysis of properties characterizing functional sequence variants located in promoter regions of genes. RES...
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Publicado no: | PeerJ |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
PeerJ Inc.
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6275119/ https://ncbi.nlm.nih.gov/pubmed/30519505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5742 |
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