Transfection of T-Box Transcription Factor BRACHYURY and SOX2 Synergistically Promote Self-Renewal and Invasive Phenotype in Oral Cancer Cells

Recent studies suggest that epithelial–mesenchymal transition (EMT) correlates with cancer metastasis. In addition, there is growing evidence of the association of EMT with cancer stem cells (CSCs). Recently, we showed that the T-box transcription factor BRACHYURY could be a strong regulator of EMT...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Akimoto, Naonari, Nakamura, Kodai, Hijioka, Hiroshi, Kume, Kenichi, Matsumura, Yoshiaki, Sugiura, Tsuyoshi
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275038/
https://ncbi.nlm.nih.gov/pubmed/30453543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113620
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