Age- and Genotype-Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in Drosophila melanogaster

The angiotensin-converting enzyme (ACE) is a peptidase that is involved in the synthesis of Angiotensin II, the bioactive component of the renin-angiotensin system. A growing body of literature argues for a beneficial impact of ACE inhibitors (ACEi) on age-associated metabolic disorders, mediated by...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Ederer, Karis A., Jin, Kelly, Bouslog, Sarah, Wang, Lu, Gorman, Gregory S., Rowe, Glenn C., Abadir, Peter, Raftery, Daniel, Moellering, Douglas, Promislow, Daniel, Jumbo-Lucioni, Patricia, De Luca, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274988/
https://ncbi.nlm.nih.gov/pubmed/30373167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113351
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