Molecular Docking, Computational, and Antithrombotic Studies of Novel 1,3,4-Oxadiazole Derivatives

A new series of 1,3,4-oxadiazoles derivatives was synthesized, characterized, and evaluated for their in vitro and in vivo anti-thrombotic activity. Compounds (3a–3i) exhibited significant clot lysis with respect to reference drug streptokinase (30,000 IU), and enhanced clotting time (CT) values (13...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Batool, Majda, Tajammal, Affifa, Farhat, Firdous, Verpoort, Francis, Khattak, Zafar A. K., Mehr-un-Nisa, Shahid, Muhammad, Ahmad, Hafiz Adnan, Munawar, Munawar Ali, Zia-ur-Rehman, Muhammad, Asim Raza Basra, Muhammad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274789/
https://ncbi.nlm.nih.gov/pubmed/30445728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113606
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