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Reconstituted HDL (Milano) Treatment Efficaciously Reverses Heart Failure with Preserved Ejection Fraction in Mice

Heart failure with preserved ejection fraction (HFpEF) represents a major unmet therapeutic need. This study investigated whether feeding coconut oil (CC diet) for 26 weeks in female C57BL/6N mice induces HFpEF and evaluated the effect of reconstituted high-density lipoprotein (HDL)(Milano) (MDCO-21...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Mishra, Mudit, Muthuramu, Ilayaraja, Aboumsallem, Joseph Pierre, Kempen, Herman, De Geest, Bart
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274776/
https://ncbi.nlm.nih.gov/pubmed/30380754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113399
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