Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes

Experimental evidence suggests that endothelin 1 (ET-1) is involved in the development of retinal microvascular abnormalities induced by diabetes. The effects of ET-1 are mediated by endothelin A- and B-receptors (ETA and ETB). Endothelin B-receptors activation mediates retinal neurodegeneration but...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bogdanov, Patricia, Simó-Servat, Olga, Sampedro, Joel, Solà-Adell, Cristina, Garcia-Ramírez, Marta, Ramos, Hugo, Guerrero, Marta, Suñé-Negre, Josep Maria, Ticó, Josep Ramon, Montoro, Bruno, Durán, Vicente, Arias, Luís, Hernández, Cristina, Simó, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274769/
https://ncbi.nlm.nih.gov/pubmed/30428543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113578
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