Loss of AMPKα2 Impairs Hedgehog-Driven Medulloblastoma Tumorigenesis

The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status that has a dual role in cancer, i.e., pro- or anti-tumorigenic, depending on the context. In medulloblastoma, the most frequent malignant pediatric brain tumor, several in vitro studies previously showed that AMPK suppress...

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Pubblicato in:Int J Mol Sci
Autori principali: Zhang, Honglai, Kuick, Rork, Park, Sung-Soo, Peabody, Claire, Yoon, Justin, Fernández, Ester Calvo, Wang, Junying, Thomas, Dafydd, Viollet, Benoit, Inoki, Ken, Camelo-Piragua, Sandra, Rual, Jean-François
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274763/
https://ncbi.nlm.nih.gov/pubmed/30360486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113287
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