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Biotherapeutics: Challenges and Opportunities for Predictive Toxicology of Monoclonal Antibodies

Biotherapeutics are a rapidly growing portion of the total pharmaceutical market accounting for almost one-half of recent new drug approvals. A major portion of these approvals each year are monoclonal antibodies (mAbs). During development, non-clinical pharmacology and toxicology testing of mAbs di...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Autor principal: Johnson, Dale E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274697/
https://ncbi.nlm.nih.gov/pubmed/30469350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113685
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