mRNA-Expression of KRT5 and KRT20 Defines Distinct Prognostic Subgroups of Muscle-Invasive Urothelial Bladder Cancer Correlating with Histological Variants

Recently, muscle-invasive bladder cancer (MIBC) has been subclassified by gene expression profiling, with a substantial impact on therapy response and patient outcome. We tested whether these complex molecular subtypes of MIBC can be determined by mRNA detection of keratin 5 (KRT5) and keratin 20 (K...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Eckstein, Markus, Wirtz, Ralph Markus, Gross-Weege, Matthias, Breyer, Johannes, Otto, Wolfgang, Stoehr, Robert, Sikic, Danijel, Keck, Bastian, Eidt, Sebastian, Burger, Maximilian, Bolenz, Christian, Nitschke, Katja, Porubsky, Stefan, Hartmann, Arndt, Erben, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274690/
https://ncbi.nlm.nih.gov/pubmed/30380731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113396
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