Beclin-1-dependent autophagy protects the heart during sepsis

BACKGROUND: Cardiac dysfunction is a major component of sepsis-induced multi-organ failure in critical care units. Changes in cardiac autophagy and its role during sepsis pathogenesis have not been clearly defined. Targeted autophagy-based therapeutic approaches for sepsis are not yet developed. MET...

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Gepubliceerd in:Circulation
Hoofdauteurs: Sun, Yuxiao, Yao, Xiao, Zhang, Qing-Jun, Zhu, Min, Liu, Zhi-Ping, Ci, Bo, Xie, Yang, Carlson, Deborah, Rothermel, Beverly A., Sun, Yuxiang, Levine, Beth, Hill, Joseph A., Wolf, Steven E., Minei, Joseph P., Zang, Qun S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274625/
https://ncbi.nlm.nih.gov/pubmed/29853517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.032821
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