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Design, Synthesis and Anticancer Evaluation of Novel Quinazoline-Sulfonamide Hybrids

By combining the structural features of quinazoline and sulfonamides, novel hybrid compounds 2–21 were synthesized using a simple and convenient method. Evaluation of these compounds against different cell lines identified compounds 7 and 17 as most active anticancer agents as they showed effectiven...

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Опубликовано в: :Molecules
Главные авторы: Ghorab, Mostafa M., Alsaid, Mansour S., Al-Dosari, Mohammed S., El-Gazzar, Marwa G., Parvez, Mohammad K.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274562/
https://ncbi.nlm.nih.gov/pubmed/26861266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020189
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