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Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy

Ursolic acid (UA), a naturally occurring pentacyclic triterpene acid found in many medicinal herbs and edible plants, triggers apoptosis in several tumor cell lines but not in human bone cancer cells. Most recently, we have demonstrated that UA exposure reduces the viability of human osteosarcoma MG...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Wu, Chia-Chieh, Huang, Yi-Fu, Hsieh, Chen-Pu, Chueh, Pin-Ju, Chen, Yao-Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274426/
https://ncbi.nlm.nih.gov/pubmed/27916903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121640
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