Two Trichothecene Mycotoxins from Myrothecium roridum Induce Apoptosis of HepG-2 Cells via Caspase Activation and Disruption of Mitochondrial Membrane Potential

Trichothecene mycotoxins are a type of sesquiterpenoid produced by various kinds of plantpathogenic fungi. In this study, two trichothecene toxins, namely, a novel cytotoxic epiroridin acid and a known trichothecene, mytoxin B, were isolated from the endophytic fungus Myrothecium roridum derived fro...

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Bibliographic Details
Published in:Molecules
Main Authors: Ye, Wei, Chen, Yuchan, Li, Haohua, Zhang, Weimin, Liu, Hongxin, Sun, Zhanghua, Liu, Taomei, Li, Saini
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274335/
https://ncbi.nlm.nih.gov/pubmed/27322225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21060781
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