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Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides

The stereoselective reduction of imines with trichlorosilane catalyzed by chiral Lewis bases is a well-established procedure for the synthesis of enantio-enriched amines. Five supported cinchona-based picolinamides have been prepared and their activity tested in a model reaction. The comparison of d...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Fernandes, Sílvia D., Porta, Riccardo, Barrulas, Pedro C., Puglisi, Alessandra, Burke, Anthony J., Benaglia, Maurizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274114/
https://ncbi.nlm.nih.gov/pubmed/27608000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21091182
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