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Synthesis and Cytotoxic Activity of Biphenylurea Derivatives Containing Indolin-2-one Moieties

In our endeavor towards the development of potent anticancer agents, two different sets of biphenylurea-indolinone conjugates, 5a–s and 8a,b were synthesized. The in vitro cytotoxicity of the synthesized compounds was examined in two human cancer cell lines, namely MCF-7 breast cancer and PC-3 prost...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Eldehna, Wagdy M., Fares, Mohamed, Ibrahim, Hany S., Alsherbiny, Muhammad A., Aly, Mohamed H., Ghabbour, Hazem A., Abdel-Aziz, Hatem A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274071/
https://ncbi.nlm.nih.gov/pubmed/27294903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21060762
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