Design, Synthesis and Antibacterial Evaluation of Some New 2-Phenyl-quinoline-4-carboxylic Acid Derivatives

A series of new 2-phenyl-quinoline-4-carboxylic acid derivatives was synthesized starting from aniline, 2-nitrobenzaldehyde, pyruvic acid followed by Doebner reaction, amidation, reduction, acylation and amination. All of the newly-synthesized compounds were characterized by (1)H-NMR, (13)C-NMR and...

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Bibliographic Details
Published in:Molecules
Main Authors: Wang, Xiaoqin, Xie, Xiaoyang, Cai, Yuanhong, Yang, Xiaolan, Li, Jiayu, Li, Yinghan, Chen, Wenna, He, Minghua
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273947/
https://ncbi.nlm.nih.gov/pubmed/26978336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21030340
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