The Prodrug Approach: A Successful Tool for Improving Drug Solubility

Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their toxicity. A lack of solubility is one of the main obstacles to drug developme...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Jornada, Daniela Hartmann, dos Santos Fernandes, Guilherme Felipe, Chiba, Diego Eidy, de Melo, Thais Regina Ferreira, dos Santos, Jean Leandro, Chung, Man Chin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273601/
https://ncbi.nlm.nih.gov/pubmed/26729077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21010042
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