Bioadhesive Surfactant Systems for Methotrexate Skin Delivery

Methotrexate (MTX) is an immunosuppressive drug for systemic use in the treatment of skin diseases, however, MTX presents a number of side effects, such as hepatotoxicity. To overcome this limitation, this study developed skin MTX delivery surfactant systems, such as a microemulsion (ME) and a liqui...

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Veröffentlicht in:Molecules
Hauptverfasser: Cintra, Giovana Aparecida de Souza, Pinto, Larissa Alvarenga, Calixto, Giovana Maria Fioramonti, Soares, Christiane Pienna, Von Zuben, Eliete de Souza, Scarpa, Maria Virgínia, Gremião, Maria Palmira Daflon, Chorilli, Marlus
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273544/
https://ncbi.nlm.nih.gov/pubmed/26901183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020231
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