Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity

A series of novel xylitan derivatives derived from xylitol were synthesized using operationally simple procedures. A xylitan acetonide was the key intermediate used to prepare benzoate, arylsulfonate esters and 1,2,3-triazole derivatives of xylitan. These compounds were evaluated for their in vitro...

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Publicado no:Molecules
Main Authors: Elias, Paula Regina, Coelho, Gleicekelly Silva, Xavier, Viviane Flores, Sales Junior, Policarpo Ademar, Romanha, Alvaro José, Murta, Silvane Maria Fonseca, Carneiro, Claudia Martins, Camilo, Nilton Soares, Hilário, Flaviane Francisco, Taylor, Jason Guy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273285/
https://ncbi.nlm.nih.gov/pubmed/27735872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101342
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