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3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus

We previously reported that the citrus flavonoid 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF) increased the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of a transient global ischemia mouse model. Since the BDNF hypothesis of depression postulates that a reduction in BDNF i...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Sawamoto, Atsushi, Okuyama, Satoshi, Yamamoto, Kana, Amakura, Yoshiaki, Yoshimura, Morio, Nakajima, Mitsunari, Furukawa, Yoshiko
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273269/
https://ncbi.nlm.nih.gov/pubmed/27120588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040541
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