Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics

Since many glycoside compounds in natural products are hydrolyzed by intestinal microbiota when administered orally, it is of interest to know whether their pharmacological effects are derived from the glycoside itself or from the aglycone form in vivo. An interesting example is baicalin versus baic...

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Detalhes bibliográficos
Publicado no:Molecules
Principais autores: Noh, Keumhan, Kang, Youra, Nepal, Mahesh Raj, Jeong, Ki Sun, Oh, Do Gyeong, Kang, Mi Jeong, Lee, Sangkyu, Kang, Wonku, Jeong, Hye Gwang, Jeong, Tae Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273104/
https://ncbi.nlm.nih.gov/pubmed/26978333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21030337
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