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A Potential Mechanism for the Anti-Apoptotic Property of Koumine Involving Mitochondrial Pathway in LPS-Mediated RAW 264.7 Macrophages

Koumine is a kind of alkaloid extracted from Gelsemium elegans (G. elegans). Benth, which has shown promise as an anti-tumor, anxiolytic, and analgesic agent. In our present study, the effect of koumine on lipopolysaccharide (LPS)-mediated RAW 264.7 cell apoptosis was evaluated. MTT assays showed th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yuan, Zhi-Hang, Liang, Zeng-Enni, Wu, Jing, Yi, Jin-E, Chen, Xiao-Jun, Sun, Zhi-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273091/
https://ncbi.nlm.nih.gov/pubmed/27706063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101317
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