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Ring-Opening Polymerization of ε-Caprolactone Initiated by Ganciclovir (GCV) for the Preparation of GCV-Tagged Polymeric Micelles

Ganciclovir (GCV) is a nucleoside analogue with antiviral activity against herpes viral infections, and the most widely used antiviral to treat cytomegalovirus infections. However, the low bioavailability and short half-life of GCV necessitate the development of a carrier for sustained delivery. In...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Sawdon, Alicia J., Peng, Ching-An
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272954/
https://ncbi.nlm.nih.gov/pubmed/25675152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022857
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