Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug

Reactions of ethylidenethiocarbohydrazide with hydrazonoyl halides gave 1,3-thiazole or 1,3,4-thiadiazole derivatives according to the type of hydrazonoyl halides. Treatment of ethylidenethiosemicarbazide with hydrazonoyl halides and dimethylacetylene dicarboxylate (DMAD) afforded the corresponding...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Gomha, Sobhi M., Salaheldin, Taher A., Hassaneen, Huwaida M. E., Abdel-Aziz, Hassan M., Khedr, Mohammed A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272888/
https://ncbi.nlm.nih.gov/pubmed/26703554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21010003
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