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Identification of Metabolites of 6′-Hydroxy-3,4,5,2′,4′-pentamethoxychalcone in Rats by a Combination of Ultra-High-Performance Liquid Chromatography with Linear Ion Trap-Orbitrap Mass Spectrometry Based on Multiple Data Processing Techniques

In this study, an efficient strategy was established using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry (UHPLC-LTQ-Orbitrap MS) to profile the in vivo metabolic fate of 6′-hydroxy-3,4,5,2′,4′-pentamethoxychalcone (PTC) in rat urine and feces. T...

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Опубликовано в: :Molecules
Главные авторы: Liu, Siyi, Che, Yanyun, Wang, Fei, Shang, Zhanpeng, Lu, Jianqiu, Dai, Shengyun, Zhang, Jiayu, Cai, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272839/
https://ncbi.nlm.nih.gov/pubmed/27669199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101266
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