Test Feasibility of Next-Generation Sequencing Assays in Clinical Mutation Detection of Small Biopsy and Fine Needle Aspiration Specimens

Objectives: To evaluate preanalytic factors contributing to failure of next-generation sequencing (NGS) assays. Methods: AmpliSeq Cancer Hotspot Panel was conducted in 1,121 of 1,152 formalin-fixed paraffin-embedded tissues submitted to a clinical laboratory, including 493 small biopsy or fine needl...

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Publicado en:Am J Clin Pathol
Main Authors: Zheng, Gang, Tsai, Harrison, Tseng, Li-Hui, Illei, Peter, Gocke, Christopher D., Eshleman, James R., Netto, George, Lin, Ming-Tseh
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272811/
https://ncbi.nlm.nih.gov/pubmed/27247373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcp/aqw043
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