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NKCS, a Mutant of the NK-2 Peptide, Causes Severe Distortions and Perforations in Bacterial, But Not Human Model Lipid Membranes

NKCS is an improved mutant of the bioactive peptide NK-2, which shows strong activity against Escherichia coli and low toxicity towards human cells. The different activity demonstrates the relevance of the physico-chemical nature of the target membrane for the biological effect of this peptide. We s...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Ciobanasu, Corina, Rzeszutek, Agnieszka, Kubitscheck, Ulrich, Willumeit, Regine
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272639/
https://ncbi.nlm.nih.gov/pubmed/25913932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20046941
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