Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu

Macromolecular crowding is known to affect protein folding, binding of small molecules, interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein aggregation. Although for a long time it was believed that the major mechanism of the action of crowded environments o...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Kuznetsova, Irina M., Zaslavsky, Boris Y., Breydo, Leonid, Turoverov, Konstantin K., Uversky, Vladimir N.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272634/
https://ncbi.nlm.nih.gov/pubmed/25594347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20011377
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