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Novel All Trans-Retinoic Acid Derivatives: Cytotoxicity, Inhibition of Cell Cycle Progression and Induction of Apoptosis in Human Cancer Cell Lines

Owing to the pharmacological potential of ATRA (all trans-retinoic acid), a series of retinamides and a 1-(retinoyl)-1,3-dicyclohexylurea compound were prepared by reacting ATRA with long chain alkyl or alkenyl fatty amines by using a 4-demethylaminopyridine (DMAP)-catalyzed N,N'-dicyclohexylca...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Al-Sheddi, Ebtesam Saad, Al-Oqail, Mai Mohammad, Saquib, Quaiser, Siddiqui, Maqsood Ahmed, Musarrat, Javed, Al-Khedhairy, Abdulaziz Ali, Farshori, Nida Nayyar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272518/
https://ncbi.nlm.nih.gov/pubmed/25961160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20058181
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