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Low-Quality Structural and Interaction Data Improves Binding Affinity Prediction via Random Forest

Docking scoring functions can be used to predict the strength of protein-ligand binding. It is widely believed that training a scoring function with low-quality data is detrimental for its predictive performance. Nevertheless, there is a surprising lack of systematic validation experiments in suppor...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Hongjian, Leung, Kwong-Sak, Wong, Man-Hon, Ballester, Pedro J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272292/
https://ncbi.nlm.nih.gov/pubmed/26076113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200610947
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