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In Vitro and in Vivo Evaluation of Novel Cross-Linked Saccharide Based Polymers as Bile Acid Sequestrants

Bile acid sequestrants (BAS) represent a therapeutic approach for the management of hypercholesterolemia that relies on the cationic polymeric nature of BAS to selectively bind negatively charged bile acids. We hypothesized that the cross-linking of β-cyclodextrin (β-CD) and saccharides such as star...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Lopez-Jaramillo, Francisco Javier, Giron-Gonzalez, Maria Dolores, Salto-Gonzalez, Rafael, Hernandez-Mateo, Fernando, Santoyo-Gonzalez, Francisco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272277/
https://ncbi.nlm.nih.gov/pubmed/25719741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20033716
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