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Synthesis, Molecular Structure and Spectroscopic Investigations of Novel Fluorinated Spiro Heterocycles

This paper describes an efficient and regioselective method for the synthesis of novel fluorinated spiro-heterocycles in excellent yield by cascade [5+1] double Michael addition reactions. The compounds 7,11-bis(4-fluorophenyl)-2,4-dimethyl- 2,4-diazaspiro[5.5] undecane-1,3,5,9-tetraone (3a) and 2,4...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Islam, Mohammad Shahidul, Al-Majid, Abdullah Mohammed, Barakat, Assem, Soliman, Saied M., Ghabbour, Hazem A., Quah, Ching Kheng, Fun, Hoong-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272187/
https://ncbi.nlm.nih.gov/pubmed/25961163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20058223
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