FBXW7 modulates malignant potential and cisplatin‐induced apoptosis in cholangiocarcinoma through NOTCH1 and MCL1

The ubiquitin ligase F‐box and WD repeat domain‐containing 7 (FBXW7) is responsible for degrading diverse oncoproteins and is considered a tumor suppressor in many human cancers. Inhibiting FBXW7 enhances the malignant potential of several cancers. In this study, we aimed to investigate the role of...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Mori, Akiko, Masuda, Kunihiro, Ohtsuka, Hideo, Shijo, Masahiro, Ariake, Kyohei, Fukase, Koji, Sakata, Naoaki, Mizuma, Masamichi, Morikawa, Takanori, Hayashi, Hiroki, Nakagawa, Kei, Motoi, Fuyuhiko, Naitoh, Takeshi, Fujishima, Fumiyoshi, Unno, Michiaki
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272118/
https://ncbi.nlm.nih.gov/pubmed/30302867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13829
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