Fibroblast growth factor receptor 3‐mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition

Recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) has been a longstanding challenge for head and neck oncologists, and current treatments still have limited efficacy. ERK is aberrantly overexpressed and activated in HNSCC. Herein, we aimed to investigate the cause of the limited...

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Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Ban, Myung Jin, Byeon, Hyung Kwon, Yang, Yeon Ju, An, Sojung, Kim, Jae Wook, Kim, Ji‐Hoon, Kim, Da Hee, Yang, Jaemoon, Kee, Hyunjung, Koh, Yoon Woo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272115/
https://ncbi.nlm.nih.gov/pubmed/30343534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13839
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