Fibroblast growth factor receptor 3‐mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition

Recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) has been a longstanding challenge for head and neck oncologists, and current treatments still have limited efficacy. ERK is aberrantly overexpressed and activated in HNSCC. Herein, we aimed to investigate the cause of the limited...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ban, Myung Jin, Byeon, Hyung Kwon, Yang, Yeon Ju, An, Sojung, Kim, Jae Wook, Kim, Ji‐Hoon, Kim, Da Hee, Yang, Jaemoon, Kee, Hyunjung, Koh, Yoon Woo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272115/
https://ncbi.nlm.nih.gov/pubmed/30343534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13839
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