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Epigenetic biomarkers of promoter DNA methylation in the new era of cancer treatment

Promoter DNA methylation, which occurs on cytosine nucleotides across CpG islands, results in gene silencing and represents a major epigenetic alteration in human cancer. Methylation‐specific PCR can amplify these modifications as markers in cancer cells. In the present work, we rigorously review th...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Yamashita, Keishi, Hosoda, Kei, Nishizawa, Nobuyuki, Katoh, Hiroshi, Watanabe, Masahiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272087/
https://ncbi.nlm.nih.gov/pubmed/30264476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13812
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