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Epigenetic biomarkers of promoter DNA methylation in the new era of cancer treatment
Promoter DNA methylation, which occurs on cytosine nucleotides across CpG islands, results in gene silencing and represents a major epigenetic alteration in human cancer. Methylation‐specific PCR can amplify these modifications as markers in cancer cells. In the present work, we rigorously review th...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272087/ https://ncbi.nlm.nih.gov/pubmed/30264476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13812 |
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