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Moderate aerobic exercise training decreases middle-aged induced pathologic cardiac hypertrophy by improving Klotho expression, MAPK signaling pathway, and oxidative stress status in Wistar rats

OBJECTIVE(S): This study aimed to investigate the effect of aerobic training on serum levels of Klotho, cardiac tissue levels of H(2)O(2) and phosphorylation of ERK1/2 and P38 as well as left ventricular internal diameter (LVID), the left ventricle wall thickness (LVWT) and fibrosis in middle-aged r...

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Bibliografiske detaljer
Udgivet i:Iran J Basic Med Sci
Main Authors: Baghaiee, Behrouz, Karimi, Pouran, Siahkouhian, Marefat, Pescatello, Linda S
Format: Artigo
Sprog:Inglês
Udgivet: Mashhad University of Medical Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272071/
https://ncbi.nlm.nih.gov/pubmed/30524691
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