Goniolactone C, a Styryl Lactone Derivative, Inhibits PDGF-BB-Induced Vascular Smooth Muscle Cell Migration and Proliferation via PDGFR/ERK Signaling

Platelet-derived growth factor-BB (PDGF-BB) and its downstream effector, extracellular signal-regulated kinase 1/2 (ERK1/2) MAP kinase, initiate a multitude of biological effects, including vascular smooth muscle cell (VSMC) proliferation and migration, which are critical events in the initiation an...

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Publicat a:Molecules
Autors principals: Sun, Lan, Zhao, Rui, Lan, Xi, Chen, Ruoyun, Wang, Si, Du, Guanhua
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271974/
https://ncbi.nlm.nih.gov/pubmed/25432005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191219501
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