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In Vitro Inhibitory Effects of Scutellarin on Six Human/Rat Cytochrome P450 Enzymes and P-glycoprotein

Inhibition of cytochrome P450 (CYP) and P-glycoprotein (P-gp) are regarded as the most frequent and clinically important pharmacokinetic causes among the various possible factors for drug-drug interactions. Scutellarin is a flavonoid which is widely used for the treatment of cardiovascular diseases....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Han, Yong-Long, Li, Dan, Yang, Quan-Jun, Zhou, Zhi-Yong, Liu, Li-Ya, Li, Bin, Lu, Jin, Guo, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271944/
https://ncbi.nlm.nih.gov/pubmed/24802986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19055748
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