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Novel [(99m)TcN](2+) Labeled EGFR Inhibitors as Potential Radiotracers for Single Photon Emission Computed Tomography (SPECT) Tumor Imaging

The epidermal growth factor receptor (EGFR) is overexpressed in many cancers, including breast, ovarian, endometrial and non-small cell lung cancer. An EGFR-specific imaging agent could facilitate clinical evaluation of primary tumors or metastases. To achieve this goal, 4-(2-aminoethylamino)-6,7-di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Zhao, Mingxia, Ning, Hongyu, Feng, Man, Li, Shilei, Chang, Jin, Qi, Chuanmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271938/
https://ncbi.nlm.nih.gov/pubmed/24786689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19055508
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