Five Withanolides from the Leaves of Datura metel L. and Their Inhibitory Effects on Nitric Oxide Production

Four new withanolides named dmetelins A–D (compounds 1–4), along with the known compound 7α,27-dihydroxy-1-oxo-witha-2,5,24-trienolide (5) were isolated from the leaves of Datura metel L. (Solanaceae). Their structures were elucidated on the basis of detailed analysis of 1D and 2D NMR and mass spect...

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Pubblicato in:Molecules
Autori principali: Yang, Bing-You, Guo, Rui, Li, Ting, Liu, Yan, Wang, Chang-Fu, Shu, Zun-Peng, Wang, Zhi-Bin, Zhang, Jing, Xia, Yong-Gang, Jiang, Hai, Wang, Qiu-Hong, Kuang, Hai-Xue
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271864/
https://ncbi.nlm.nih.gov/pubmed/24731984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19044548
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